Zhang Neuroscience Research Laboratories Publications

Recent Publications

Below are several references to recent publications from our lab. Additional references can be found in the online CVs of lab personnel.

2008

Editor for Book

Hyperbaric Oxygen on Neurological Diseases. Editor: John H. Zhang. Best Publishing. 2008

Advances of Clinical Neurological Research. Editor: John H. Zhang. Research Signpost, 2008

Animal Models of Acute Neurological Injury. Editors: Jun Chen, Xiaoming Xu, Zao C. Xu, John H. Zhang. Humana 2008

Editor for Special Journal Issue

J.H. Zhang: Chinese Neurosurgery Research. Neurological Research July 2008

J.H. Zhang: Frontiers of Neurosurgery Research. Frontiers in Bioscience January 2008

Original Article:

G. Gu, Y. Li, Z. Peng, J. Xu, Z. Kang, W. Xu, H. Tao, R. P. Ostrowski, J. H. Zhang , X. Sun. Mechanism of ischemic tolerance induced by hyperbaric oxygen preconditioning involves up-regulation of hypoxia-inducible factor-1alph and erythropoietin in rats. J Applied Physiol In press

Z. Li, W. Liu, Z. Kang, L. Yun, X. Sun, J.H. Zhang. Mechanism of hyperbaric oxygen preconditioning in neonatal hypoxia-ischemia rat model. Brain Research

S. Zhang, Q. Zhang, J. Zhang, X. Qin. Electro-stimulation of Cerebellar Fastigial Nucleus (FNS) Improves Axonal Regeneration. Frontiers in Bioscience. 2007

W. Liu, X. Sun, K, Liu, J.H. Zhang, W. Xu, H. Tao. Repetitive Hyperbaric Oxygen Exposures Enhance Sensitivity to Convulsion by Upregulation of eNOS and nNOS. Brain Research

Review

V. Jadhav, J. Zhang. Surgical Brain Injury: Prevention is better than Cure. Front Biosci. 2008

S. Zhang, Q. Zhang, J.H. Zhang, X. Qin. NgR Acts as an Inhibitor to Axonal Regeneration in Adults. Front Biosci 13: 2030-2040. 2008

T. Lekic, J.H. Zhang. Posterior Circulation Stroke and Animal Models. Front Biosci 13: 1827-1844, 2008

Editorial

J. Zhang. Introduction to Special Issue: Chinese Neurosurgery Research. Neurological Research 2008

Y. Zhang, J. Zhang. Dr. Chongchuang Wang and Beijing Neurosurgical Institute. Neurological Research 2008

J. Zhang. Editor’s Remark: Hyperbaric Oxygen on Neurological Diseases. Ed: J.H. Zhang. Best Publishing 2008

J. Chen, X. Xu, J. Xu, J. Zhang. Preface. Animal Models of Acute Neurological Injury. Ed: J. Chen, X. Xu, J. Xu, J. Zhang. Humana 2008

J. Zhang. Preface: Advances of Neurological Research. Ed: J. Zhang. Research Signpost. 2008

Journal Supplement

S. Lee, G. Stier, S. Marcantonio, T. Lekic, M. Allard, R. Martin, J. Zhang. Effects Of 3% Hypertonic Saline on Brain Edema and Neurologic Function Following Subarachnoid Hemorrhage In Rats. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 2008

S. Lee, V. Jadhav, R. Ayer, T. Lekic, A. Hyong, M. Allard, G. Stier, R. Martin, J. Zhang. The Effects of Simvastatin In Surgically Induced Brain Injury In Rats. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 2008

S. Lee, V. Jadhav, R. Ayer, T. Lekic, A. Hyong, G. Stier, R. Martin, J. Zhang. The Antioxidant Effects of Melatonin in Surgically Induced Brain Injury in Rats. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 2008

V. Jadhav, M. Yamaguchi, A. Obenaus, J. Zhang. MMP Inhibition Attenuates Brain Edema in Surgically-Induced Brain Injury. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 2008

T. Sugawara, V. Jadhav, J. Zhang. Simvastatin Attenuates Cerebral Vasospasm and Improves Outcome after Subarachnoid Hemorrhage. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 2008

W. Chen, V. Jadhav, J. Tang, J. Zhang. HIF-1α Inhibition Ameliorates Neonatal Brain Injury in Hypoxic-ischemic Rat Pup Model. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 2008

R. E. Ayer, J. Zhang. Melatonin Decreases Mortality Following Subarachnoid Hemorrhage. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 2008

E. Titova, R. Ostrowski, J. Rowe, J. Zhang, J. Tang. Effects of Lecithinized Superoxide Dismutase and Catalase on Intracerebral Hemorrhage-induced Brain Injury in Rats. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 2008

E. Titova, C. Kevil, H. Rojas, L. Sowers, J. Zhang, J. Tang. Deficiency of CD 18 Gene Reduces Brain Edema in Experimental Intracerebral Hemorrhage in Mice. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 2008

E. Titova, R. Ostrowski, J. Zhang, J. Tang. Effects of Amantadine Sulphate on Intracerebral Hemorrhage-induced Brain Injury in Rats. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 2008

T. Lekic, J. Tang, J. Zhang. A Rat Model of Intracerebellar Hemorrhage. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 2008

T. Lekic, H. Rojas, J. Tang, J. Zhang. A Rat Model of Pontine Hemorrhage. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 2008

H. A. Rojas, R. Ayer, W. Chen, S. Lee, V. Jadhav, E. Titova, R. Martin, R. Hartman, J. Tang, J. Zhang. Long Term Effects of Melatonin after Intracerebral Hemorrhage in Rats. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 2008

H. A. Rojas, T. Lekic, W. Chen, V. Jadhav, E. Titova, R. Martin, J. Tang, J. Zhang. The Antioxidant Effects of Melatonin after Intracerebral Hemorrhage in Rats. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 2008

R. Hartman, H. Rojas, J. Zhang. Longitudinal Behavioral Characterization of a Rat Model of ICH. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 2008

Book Chapter

J. Cahill, J. Zhang. Early Brain Injury and the Role of Apoptosis after a Subarachnoid Hemorrhage. Advances of Clinical Neurological Research. Ed: J.H. Zhang. Research SignPost 2008

G. A. Matchett, C. Higuchi, M. Allard, R. Martin, J. Zhang. Volatile Anesthetics and Cerebral Ischemia: Neuroprotective Mechanisms, Clinical Implications. Ed: J.H. Zhang. Research SignPost 2008

G.A. Matchett, R. Martin, J. Zhang. Hyperbaric Oxygen Therapy and Cerebral Ischemia. Ed: J.H. Zhang. Research SignPost 2008

R. P. Ostrowski, J. Zhang. Mechanisms of Hyperbaric Oxygen in Neurological Disorders. Hyperbaric Oxygen Therapy for Neurological Diseases. Ed: J.H. Zhang. Best Publishing 2008

P. Ren, X.J. Sun, J. H. Zhang. Hyperbaric Oxygen for Carbon Monoxide Poisoning. Hyperbaric Oxygen Therapy for Neurological Diseases. Ed: J.H. Zhang. Best Publishing 2008

J. Cahill, J. Zhang. Invasive Cerebral Blood Flow and Blood Pressure Monitoring In the Rodent Model. Animal Models of Acute Neurological Injury. Ed: J. Chen, X. Xu, J. Xu, J. Zhang. Humana 2008

R. Ayer, J. Cahill, T. Sugawara, V. Jadhav, J. Zhang. Surgical Procedures and Care. Animal Models of Acute Neurological Injury. Ed: J. Chen, X. Xu, J. Xu, J. Zhang. Humana 2008

J. Cahill, J. Zhang. The Monofilament Puncture Model for the Induction of a Subarachnoid Hemorrhage in the Rodent. Animal Models of Acute Neurological Injury. Ed: J. Chen, X. Xu, J. Xu, J. Zhang. Humana 2008

2007

Editor for Book

Cerebral Vasospasm IX. Editors: Talat Kiris, John H. Zhang. Springer Wien New York. 2007

Editor for Special Journal Issue

J.H. Zhang: Hyperbaric Oxygen on Neurological Disorders. Neurological Research 29 (2) March 2007

Original Article

J. Cahill, J. Calvert, S. Marcantonio & J. Zhang. P53 May Play an Orchestrating Role in Apoptotic Cell Death after Experimental SAH. Neurosurgery 60: 531-545, 2007 http://dx.doi.org/10.1227/01.NEU.0000249287.99878.9B

V. Jadhav, I. Solaroglu, A. Obenaus, J. H. Zhang. Neuroprotection against Surgically Induced Brain Injury. Surgical Neurology 67:15-20, 2007 http://dx.doi.org/10.1016/j.surneu.2006.07.014

V. Jadhav, G. Matchett, F. P. Hsu & J.H. Zhang. Inhibition of Src tyrosine kinase and effect on outcomes in a new in vivo model of surgically induced brain injury. J Neurosurg. 2007 Apr;106(4):680-6.

J. Calvert & J. Zhang. Oxygen Treatment Restores Energy Status following Experimental Neonatal Hypoxia-Ischemia. Pediatric Critical Care Med 8: 165-173, January 2007 http://dx.doi.org/10.1097/01.PCC.0000257113.75488.84

T. Tsubokawa, V. Jadhav, I. Solaroglu, Y. Shiokawa, Y. Konishi & J. Zhang. Lecithinized Superoxide Dismutase Attenuates Focal Cerebral Ischemic Injury via Anti-Apoptotic Mechanisms in Rats. Stroke 38: 1057-1062, February 2007 http://dx.doi.org/10.1161/01.STR.0000257978.70312.1d

G. Matchett, J. Calinisan, G. Matchett, R. Martin & J. Zhang. The Effect of Granulocyte-Colony Stimulating Factor in Global Cerebral Ischemia in Rats. Brain Research 1136: 200-207, 2007 http://dx.doi.org/10.1016/j.brainres.2006.12.023

W. Lo, T. Brava, V. Jadhav, J. Zhang, J. Tang. NADPH Oxidase Inhibition Improves Neurological Outcomes in Surgically-induced Brain Injury. Neuroscience Lett 414: 228-232, 2007 http://dx.doi.org/10.1016/j.neulet.2006.12.055

H. Yatsushige, R. Ostrowski, T. Tsubokawa, A. Colohan, J.H. Zhang. Role of c-Jun N-terminal Kinase in Early Brain Injury after SAH. J Neurosci Res 85: 1436-1448, 2007 http://dx.doi.org/10.1002/jnr.21281

K. Yata, G. Matchett, T. Tsubokawa, J. Tang, K.Kanamaru & J.H. Zhang. Granulocyte-Colony Stimulating Factor Inhibits Apoptotic Neuron Loss after Neonatal Hypoxia-Ischemia in Rats. Brain Research 1145: 227-238, 2007 http://dx.doi.org/10.1016/j.brainres.2007.01.144

Z. Huang, Z. Kang, G. Gu, G. Peng, Y. Liu, H. Tao, W. Xu, J.H. Zhang, X. Sun. Therapeutic Effects of Hyperbaric Oxygen in a Rat Model of Endothelin-1 Induced Focal Cerebral Ischemia. Brain Research 1153: 204-213, 2007 http://dx.doi.org/10.1016/j.brainres.2007.03.061

E. Titova, R.P. Ostrowski, L.C. Sowers, J.H. Zhang, J. Tang. Effects of Apocynin and Ethanol on Intracerebral Hemorrhage-Induced Brain Injury in Rats. Clin Exp Pharmacol Physiol 34(9): 845-850, 2007

D. Zhou, G. Matchett, V. Jadhav, N. Dach & J. Zhang. The Effect of 2-Methoxyestradiol, a HIF-1α Inhibitor, in Global Cerebral Ischemia in Rats. Neurological Research Aug 22, 2007

S. Liu, J. Tang, R. Ostrowski, E. Titova, C. Monroe, W. Chen, W. Lo, R. Martin, J. Zhang. Oxidative Stress after SAH in gp91phox Knockout Mice. Can J NeurolSci 34(3): 356-361, 2007

M. Yamaguchi, V. Jadhav, A. Obenaus, A. Colohan & J. Zhang. Matrix Metalloproteinase Inhibition Attenuates Brain Edema in an in vivo Model of Surgically-Induced Brain Injury. Neurosurgery 61(5): 1067-1075, 2007

R. Ostrowski, G. Graupner, E. Titova, J. Zhang, J. Chiu, N. Dach, D. Corleone, J. Tang, J. Zhang. The Hyperbaric Oxygen Preconditioning-Induced Brain Protection is mediated by A Reduction of Early Apoptosis after Transient Global Cerebral Ischemia. Neurobiology of Disease 29(1): 1-13, Jul 28, 2007

T. Sugawara, R. Ayer, V. Jadhav, J. H. Zhang. A New Grading System Evaluating Bleeding Scale in Filament Perforation Subarachnoid Hemorrhage Rat Model. J Neurosci Methods 167(2): 327-334, Aug 12, 2007

R. Ayer, T. Sugawara, W. Chen, W. Tong, J.H. Zhang. Melatonin Decreases Mortality Following Severe Subarachnoid Hemorrhage. Journal of Pineal Research

Review

R. L. Macdonald, R. Pluta, and J. H. Zhang. Cerebral Vasospasm after Subarachnoid Hemorrhage: The Emerging Revolution. Nature Clinical Practice Neurology 3(5): 256-263, 2007 http://dx.doi.org/10.1038/ncpneuro0490

J. Hansen-Schwartz, P. Vajkoczy, R. L. Macdonald, R. M. Pluta, J. H. Zhang. Cerebral Vasospasm: Looking beyond vasoconstriction. TiPS 28(6): 252-256, 2007 http://dx.doi.org/10.1016/j.tips.2007.04.002

I. Solaroglu, V. Jadhav, J.H. Zhang. Neuroprotective Effect of Granulocyte-Colony Stimulating Factor (Review). Frontiers in Biosciences 12: 712-724, 2007 http://dx.doi.org/10.2741/2095

J. W. Calvert, J.H. Zhang. HBO and Brain Physiology (Review). Neurological Research 2007 29: 132-141, 2007
E. Titova, R. Ostrowski, J.H. Zhang, J. Tang. Experimental Models of SAH for Studies of Cerebral Vasospasm. Neurological Research July 2007

J. Cahill, J. H. Zhang. Early Brain Injury after SAH (Review). The 9th International Conference on Cerebral Vasospasm. Acta Neurochirurgica Supplement 2007

S. Armin, A. Colohan, J. H. Zhang. Vasospasm in Traumatic Brain Injury (Review). The 9th International Conference on Cerebral Vasospasm. Acta Neurochirurgica Supplement 2007

R.E. Ayer, J.H. Zhang. Oxidative Stress in SAH: Significance in Acute Brain Injury and Vasospasm. The 9th International Conference on Cerebral Vasospasm. Acta Neurochirurgica Supplement 2007

T. Sugawara, R. Ayer, J.H. Zhang. Role of Statins in Cerebral Vasospasm. The 9th International Conference on Cerebral Vasospasm. Acta Neurochirurgica Supplement 2007

Editorial

R. Ayer, J.H. Zhang. Comment on: Neural Stem Cell Markers, Nestin and Musashi Proteins, in Progression of Human Glioma: Correlation of Nestin with Prognosis of Patient Survival. Surgical Neurology 68: 143-144, 2007

J.H. Zhang. Introduction to Special Issue: Hyperbaric Oxygen on Neurological Diseases. Neurological Research 29: 113-115, 2007

J. Hansen-Schwartz & J.H. Zhang. Cerebral Vasospasm Revisited - A Conference Where East Meets West. International Journal of Stroke 2: 2-3, 2007 http://dx.doi.org/10.1111/j.1747-4949.2007.00082.x

T. Kiris, J. Zhang. Preface: Cerebral Vasospasm after Subarachnoid Hemorrhage. The 9th International Conference on Cerebral Vasospasm. Springer, 2007

Journal Supplement

J. Cahill, I. Solaroglu, J.H. Zhang. Apoptotic Markers in Vasospasm after Experimental SAH. The 9th International Conference on Cerebral Vasospasm. Acta Neurochirurgica Supplement 2007

W. Shi, L. Huang, R. Wang, J. Sun, F. Wang, C. Liu, L. Zhou, J.H. Zhang. Oxyhemoglobin Induces Apoptosis in Mice Brain Cells In Vivo. The 9th International Conference on Cerebral Vasospasm. Acta Neurochirurgica Supplement 2007

H. Yatsushige, M. Yamaguchi-Okada, J. Cahill, A. Colohan, J.H. Zhang. Inhibition of c-Jun N-terminal Kinase Pathway Attenuates Cerebral Vasospasm through Suppression of Apoptosis. The 9th International Conference on Cerebral Vasospasm. Acta Neurochirurgica Supplement 2007

W. Tang, G. Zhu, J. Zhang, Z. Chen, Z. Liu, X. Wang, H. Feng. Effect of Oxyhemoglobin on Proliferation and Migration of Cultured Vascular Advential Fibroblast. The 9th International Conference on Cerebral Vasospasm. Acta Neurochirurgica Supplement 2007

Z. Liu, G. Zhu, J. Zhang, Z. Chen, W. Tang, X. Wang, H. Feng. Ecdysterone Attenuates Vasospasm following Experimental SAH in Rabbits. The 9th International Conference on Cerebral Vasospasm. Acta Neurochirurgica Supplement 2007

W. Tang, G. Zhu, J. Zhang, Z. Chen, Z. Liu, X. Wang, H. Feng. Effect of Oxyhemoglobin on Proliferation and Migration of Cultured Vascular Smooth Muscle Cells. The 9th International Conference on Cerebral Vasospasm. Acta Neurochirurgica Supplement 2007

Z. Chen, H. Feng, J.H. Zhang, W. Tang, Z. Liu, G. Zhu, X. Wang. Proliferation of Vascular Smooth Muscle Cells Following Experimental SAH and the Effect of Ecdysterone. The 9th International Conference on Cerebral Vasospasm. Acta Neurochirurgica Supplement 2007

Z. Chen, G. Zhu, J.H. Zhang, Z. Liu, W. Tang, H. Feng. Ecdysterone-Sensitive Smooth Muscle Proliferation Stimulated by Conditioned Medium of Endothelial Cells Cultured with Bloody CSF. The 9th International Conference on Cerebral Vasospasm. Acta Neurochirurgica Supplement 2007

T. Sukawara, A. Wang, V. Jadhav, A. Obenaus, & J.H. Zhang. MRI in the Canine Double-Hemorrhage SAH Model. The 9th International Conference on Cerebral Vasospasm. Acta Neurochirurgica Supplement 2007

Book Chapter

R. Ostrowski, A. Colohan, J. Zhang. Molecular Signaling Pathways in Early Brain Injury after SAH. Ed P. Chan, Hand Book of Neurochemistry and Molecular Neurobiology - Acute Ischemic Injury and Repair in the Nervous System. Pp235-253, 2007

2006

Editor for Special Journal Issue

J.H. Zhang: Subarachnoid Hemorrhage. Neurological Research 28 (4): 2006

J.H. Zhang: Cerebral Vasospasm. Neurological Research 28 (7): 2006

Original Article

R. Ostrowski, J. Tang & J.H. Zhang. HBO Suppresses NADPH Oxidase in a Rat SAH Model. Stroke 37: 1314-1318, 2006 http://dx.doi.org/10.1161/01.STR.0000217310.88450.c3

N. Shimamura, H. Yatsushige, G. Matchett, J. Calvert, H. Ohkuma & J.H. Zhang. Inhibition Of Integrin Αvβ3 Ameliorates Focal Cerebral Ischemic Damage In The Rat Middle Cerebral Artery Occlusion Model. Stroke 37: 1902-1909, 2006 http://dx.doi.org/10.1161/01.STR.0000226991.27540.f2

N. Shimamura, G. Matchett, T. Tsubokawa, H. Ohkuma, J.H. Zhang. Comparison of Silicon-coated Nylon Suture to Plain Nylon Suture in the Rat Middle Cerebral Artery Occlusion Model. J Neurosci Methods. 156: 161-165, 2006 http://dx.doi.org/10.1016/j.jneumeth.2006.02.017

J. Cahill, J. Calvert, I. Solaroglu & J.H. Zhang. Vasospasm and p53 Induced Apoptosis in an Experimental Model of Subarachnoid Hemorrhage. Stroke 37: 1868-1874, 2006 http://dx.doi.org/10.1161/01.STR.0000226995.27230.96

T. Tsubokawa, I. Solaroglu, H. Yatsushige, J. Cahill, K. Yata & J.H. Zhang. Cathepsin and Calpain Inhibitor E64d Attenuates Matrix Metaloprotease-9 Activity after Focal Cerebral Ischemia. Stroke 37: 1888-1894, 2006 http://dx.doi.org/10.1161/01.STR.0000227259.15506.24

J. Tang, I. Kusaka, A. Massey, S. Rollins, J.H. Zhang. Increased RhoA Translocation in Aorta of Diabetic Rats. Acta Pharmacologica Sinica 27: 543-548, 2006 http://dx.doi.org/10.1111/j.1745-7254.2006.00325.x

W. Shi, L. Huang, S. Wang, J. Sun, F. Wang, Z. Liu, L. Zhou, J.H. Zhang. OxyHb Produces Neuronal Apoptosis after SAH. Chinese J Neurosurg 22: 257-258, 2006

T. Tsubokawa, M. Yamaguchi-Okada, J. Calvert, I. Solaroglu, N. Shimamura, K. Yata & J. H. Zhang. Neurovascular and Neuronal Protection by E64d after Focal Cerebral Ischemia in Rats. J Neurosci Res 84: 832-840, 2006 http://dx.doi.org/10.1002/jnr.20977

J. Calvert, J. Cahill, M. Yamaguchi-Okada, J.H. Zhang. Oxygen Treatment Following Experimental Hypoxia-Ischemia alters the Expression of HIF-1alpha and its Downstream Target Genes. J Appl Physiol. 101: 853-865, 2006 http://dx.doi.org/10.1152/japplphysiol.00268.2006

G. Matchett, J. Hahn, A. Obenaus, J.H Zhang. Surgically Induced Brain Injury in Rats: Effect of EPO. J Neuroscience Method 158: 234-241, 2006 http://dx.doi.org/10.1016/j.jneumeth.2006.06.003

G. Miao, R. Ostrowski, J. Mace,, A. Hopper, R. Peverini, R. Chinnock, J.H, Zhang, E. Hathout. Dynamic Production of Hypoxia-Inducible Factor-1α in Early Transplanted Islets. Am J Transplantation 6: 2636-2643, 2006 http://dx.doi.org/10.1111/j.1600-6143.2006.01541.x

H. Yatsushige, J. Calvert, J. Cahill & J.H. Zhang. Limited Role of Inducible Nitric Oxide Synthase in Brain Barrier Function following Experimental Subarachnoid Hemorrhage. J Neurotrauma 23: 1874-1882, 2006 http://dx.doi.org/10.1089/neu.2006.23.1874

N. Shimamura, G. Matchett, I. Solaroglu, T. Tsubokawa1, H. Ohkuma, J. H. Zhang. Inhibition of integrin alphavbeta3 reduces blood-brain barrier breakdown in focal ischemia in rats. J Neurosci Res. 2006 Dec;84(8):1837-47. http://dx.doi.org/10.1002/jnr.21073

I. Solaroglu, T. Tsubokawa, J. Cahill & J.H. Zhang. Anti-apoptosis Effect of Granulocyte-Colony Stimulating Factor after Focal Cerebral Ischemia in Rats. Neuroscience (cover art) 143: 965-974, 2006 http://dx.doi.org/10.1016/j.neuroscience.2006.09.014

Review

J. Cahill, J. Calvert, J.H. Zhang. Mechanisms of Early Brain Injury after Subarachnoid Hemorrhage (Review). J Cereb Blood Flow Met 26: 1341-1353, 2006 http://dx.doi.org/10.1038/sj.jcbfm.9600283

I. Solaroglu, J. Cahill, V. Jadhav, J.H. Zhang. A Novel Neuroprotectant Granulocyte-Colony Stimulating Factor (Review). Stroke 37: 1123-1128, 2006 http://dx.doi.org/10.1161/01.STR.0000208205.26253.96

R. Ostrowski, A. Colohan, J.H. Zhang. Molecular Signaling Pathways in Early Brain Injury after SAH (Review). Neurological Research 28: 399-414, 2006

S. Armin, A. Colohan, J.H. Zhang. Traumatic Subarachnoid Hemorrhage: Our Current Understanding and its Evolution over the Past Half Century (Review). Neurological Research 28: 445-452, 2006 http://dx.doi.org/10.1179/016164106X115053

Editorial/Letter/Comment

J. H. Zhang. Introduction to Special Issue: Subarachnoid Hemorrhage. Neurological Research 28: 369-371, 2006

I. Solaroglu, J. Cahill, V. Jadhav, J.H. Zhang. Response to Letter by Schabitz et al. Stroke 37: 1655, 2006 http://dx.doi.org/10.1161/01.STR.0000227378.20245.df

J.H. Zhang. Introduction to Special Issue: Cerebral Vasospasm. Neurological Research 28: 687-689, 2006

J.H. Zhang. Pravastatin Prevents Ischemia-reperfusion Injury in Rat Sciatic Nerve. Comment. Surgical Neurology 66: 338-339, 2006

Journal Supplement

R.P. Ostrowski, A.R.T. Colohan, J.H. Zhang. Neuroprotective Effect of Hyperbaric Oxygen in a Rat Model of Subarachnoid Hemorrhage. Acta Neurochirugica Supplement 96: 188-193, 2006

2005

Editor for Special Journal Issue

J.H. Zhang: Cerebral Vascular Diseases. Pathophysiology 12: 2005

J.H. Zhang: Experimental Therapies for Stroke. Neurological Research 2005 27 (3): 2005

Original Article

Y. Li, C. Zhou, J. W. Calvert, A. Colohan, J. Zhang. Multiple Effects of HBO on HIF1alpha Expression and Apoptotic Genes in Global Ischemia Rat Model. Experimental Neurology 191: 198-210, 2005 http://dx.doi.org/10.1016/j.expneurol.2004.08.036

C. Smelley, R.D. Specian, J. Tang, J. Zhang. Gastric Ulcer after Intracranial Hemorrhage in Rats. Brain Res 1038: 198-207, 2005 http://dx.doi.org/10.1016/j.brainres.2005.01.042

M. Shaya, A. Dubey, C. Berk, E. Gonzalez-Toledo, J.H. Zhang, G. Caldito, A. Nanda. Factors Influencing Outcome in Intracerebral Hematoma: a Simple, Reliable, and Accurate method to Grade Intracerebral Hemorrhage. Surgical Neurology 63: 343-348, 2005 http://dx.doi.org/10.1016/j.surneu.2004.06.019

D. Yin, N. Tamaki, A. Parent & J. Zhang. Insulin-like Growth Factor-I Decreased Etoposide-induced Apoptosis in Glioma Cells by increasing BCl-2 Expression and Decreasing CPP32 Activity. Neurological Research 27: 27-35, 2005 http://dx.doi.org/10.1179/016164105X18151

D. Yin, J. Zhang. Delayed and Multiple Hyperbaric Oxygen Treatments Expand Therapeutic Window in Focal Cerebral Ischemia Model. NeuroCritical Care 2: 206-211, 2005 http://dx.doi.org/10.1385/NCC:2:2:206

G. Mychaskiw, J. Pan, S. Shah, A. Zubkov, B. Clower, A. Badr & J.H. Zhang. Effects of hyperbaric oxygen on skin blood flow and tissue morphology following sciatic nerve constriction. Pain Physician. 2005 Apr;8(2):157-61.

R. Ostrowski, A. Colohan & J. Zhang. Mechanisms of Hyperbaric Oxygen Induced Neuroprotection in a Rat model of Subarachnoid Hemorrhage. J Cereb Blood Flow Metab 25: 554-571, 2005 http://dx.doi.org/10.1038/sj.jcbfm.9600048

C. Zhou, M. Yamaguchi, A. Colohan, J. Zhang. Role of p53 and apoptosis in cerebral vasospasm after experimental subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2005 May;25(5):572-82. http://dx.doi.org/10.1038/sj.jcbfm.9600069

R.V. Patwardhan, W. Besio, J.W. Calvert, G. Kusaka, I. Kusaka, J. Zhang, A. Nanda. Electroconvulsive Therapy for Seizure Control: Preliminary Data in a New Seizure Generation and Control Model. Front Biosci 10: 3013-3019, 2005 http://dx.doi.org/10.2741/1758

R.V. Patwardhan, W. Besio, J.W. Calvert, G. Kusaka, I. Kusaka, J. Zhang, A. Nanda. Technical Note: Preliminary Results in Development of a Novel Intracisternal Penicillin Seizure Model in the Rat. Front Biosci 10: 3009-3012, 2005 http://dx.doi.org/10.2741/1757

Y. Sun, J. Calvert, J. Zhang. Neonatal hypoxia/ischemia is associated with decreased inflammatory mediators after erythropoietin administration. Stroke. 2005 Aug;36(8):1672-8. Epub 2005 Jul 21. http://dx.doi.org/10.1161/01.STR.0000173406.04891.8c

H. Yatsushige, M. Yamaguchi, J. Calvert, C. Zhou & J. Zhang. Role of JNK in Cerebral Vasospasm after Experimental Subarachnoid Hemorrhage. Stroke 36: 1538-1543, 2005 http://dx.doi.org/10.1161/01.STR.0000170713.22011.c8

M. Yamaguchi, J. Calvert, G. Kusaka & J. Zhang. One-stage anterior approach for four-vessel occlusion in rat. Stroke. 2005 Oct;36(10):2212-4. Epub 2005 Sep 15. http://dx.doi.org/10.1161/01.STR.0000182238.08510.c5

J. Tang, J. Liu, C. Zhou, D. Ostanin, M. Grisham, D.N. Granger & J. Zhang. Role of NADPH oxidase in the brain injury of intracerebral hemorrhage. J Neurochem. 2005 Sep;94(5):1342-50. Epub 2005 Jul 11. http://dx.doi.org/10.1111/j.1471-4159.2005.03292.x

Review

J.W. Calvert & J.H. Zhang. Pathophysiology of Hypoxia-Ischemia Insult during Perinatal Period. Neurological Research 27: 246-260, 2005 http://dx.doi.org/10.1179/016164105X25216

J. Zhang, T. Lo, G. Mychaskiw, A. Colohan. Mechanisms of Hyperbaric Oxygen and Neuroprotection in Stroke. Pathophysiology 12: 63-78, 2005 http://dx.doi.org/10.1016/j.pathophys.2005.01.003

Editorial

J.H. Zhang. Introduction to Special Issue: Experimental Therapies for Stroke. Neurological Research 2005 27: 227-228, 2005

J. Zhang. Introduction to Special Issue: Cerebral Vascular Diseases. Pathophysiology 12: 3-4, 2005

Journal Supplement

Y. Dai, J. Tang & J. Zhang. Role of Cl- in Cerebral Vascular Tone and Expression of Na+-K+-2Cl- Co-transporter after Neonatal Hypoxia-ischemia. Canadian Journal of Physiology & Pharmacology Supplemental 83: 767-773, 2005

J. Tang, S. Fitzgerald, B. Boughtman, S. Cole, M. Brands & J.H. Zhang. Decreased RhoA Expression in Myocardium of Diabetic Rats. Canadian Journal of Physiology & Pharmacology Supplemental 83: 775-783, 2005

Book Review

J. Cahill & J. Zhang. Book Review: Mechanisms of Secondary Brain Damage From Trauma and Ischemia: Recent Advances of Our Understanding. (Acta Neurochirurgica Supplement 89. A. Baethmann, J. Eriskat, J. Lehmberg and N. Plesnila, editors. New York: Springer Wien New York. 2004. 127 pp, illus. ISBN 3-211-20932-8. Price: $129.00.) J Neurosurg 102: 581, 2005

R. Ostrowski & J. Zhang. Microelectrode Recording in Movement Surgery. Zvi Israel and Kim J. Burchiel, editors. New York: Thiemes, 2004. 220 pp, illus. ISBN 1-58890-172-4. Price: $149.00. J Neurosurg 102: 755-756, 2005

J. Calver & J. Zhang. Textbook of Hyperbaric Medicine, 4th Revised and Expanded Edition. K.K. Jain. Cambridge: Hogrefe & Huber, 2004, 536 pp, illus. ISBN 0-88937-277-2. Price $139.00. J Neurosurg 102: 958, 2005

2004

Editor for Special Journal Issue

J.H. Zhang: Apoptosis in Cerebral Ischemia. Neurological Research 26 (8): 2004

Original Article

Y. Miyagi & J. Zhang. α, β-Methylene ATP Enhances P2Y4-contraction of Rabbit Basilar Artery. Am J Physiol Heart & Circulatory Physiol 286: H1546-1551, 2004 http://dx.doi.org/10.1152/ajpheart.00926.2003

Y. Miyagi, H. Kimura, R.C. Carpenter, A. Parent, J. Zhang. α,β-Methylene ATP Augments UTP-contraction of Rabbit Basilar Artery. Eur J Pharmacol 488: 117-125, 2004 (withdrawn) http://dx.doi.org/10.1016/j.ejphar.2004.02.002

Y. Sun, C. Zhou, A. Nanda, J. Zhang. Mechanism of Erythropoietin-induced Neuroprotection in Neonatal Hypoxia. J Cereb Blood Flow Metab 24: 259-270, 2004 http://dx.doi.org/10.1097/01.WCB.0000110049.43905.AC

M. Ishikawa, K. Stokes, J.H. Zhang, A. Nanda, D.N. Granger. Cerebral Microvascular Responses to Hypercholesterolemia: Roles of NADPH Oxidase and P-selectin. Circ Res 94: 239-244, 2004 http://dx.doi.org/10.1161/01.RES.0000111524.05779.60

C. Zhou, M. Yamaguchi, G. Kusaka, C. Schonholz, A. Nanda, J. Zhang. Caspase Inhibitor Prevents Endothelial Apoptosis and Cerebral Vasospasm. J Cereb Blood Flow Metab 24: 419-431, 2004 http://dx.doi.org/10.1097/00004647-200404000-00007

G. Kusaka, J.W. Calvert, C. Smelley, A. Nanda, J. Zhang. A New Lumbar Method for Monitoring Cerebrospinal Fluid Pressure in Rats. J Neurosci Methods 135: 121-127, 2004 http://dx.doi.org/10.1016/j.jneumeth.2003.12.013

A. Jawahar, F. Ampil, C. Weilbaecher, G. Hartman, J. Zhang, A. Nanda. Management Strategies for Patients with Brain Metastases: Has Radiosurgery Made a Difference? South Med J 97: 254-258, 2004 http://dx.doi.org/10.1097/01.SMJ.0000060569.47897.75

A. Jawahar, R. Matthew, A. Minagar, D. Shukla, J. Zhang, B. Willis, F. Ampil, A. Nanda. Gamma Knife Radiosurgery in the Management of Brain Metastases from Lung Carcinoma: A Retrospective Analysis of Survival, Local Tumor Control, and Freedom from New Brain Metastases. J Neurosurg 100: 842-847, 2004

I. Kusaka, G. Kusaka, C. Zhou, M. Ishikawa, A. Nanda, D.N. Granger, J. Zhang & J. Tang. Role of AT1 Receptors and NAD(P)H Oxidase in Diabetes-Aggravated Ischemic Brain Injury . Am J Physiol Heart Circ Physiol 286: 2442-2451, 2004 http://dx.doi.org/10.1152/ajpheart.01169.2003

M. Yamaguchi, C. Zhou, A. Nanda, J. Zhang. Ras Protein Contributes to Cerebral Vasospasm in a Canine Double Hemorrhage Model. Stroke 35: 1750-1755, 2004 http://dx.doi.org/10.1161/01.STR.0000129898.68350.9f

G. Kusaka, I. Kusaka, M. Ishikawa, A. Nanda, D.N. Granger, J. Zhang. Signaling Pathways for Early Brain Injury after Subarachnoid Hemorrhage. J Cereb Blood Flow Metab 24: 916-925, 2004 http://dx.doi.org/10.1097/01.WCB.0000125886.48838.7E

M. Ishikawa, D. Cooper, T.V. Arumugam, J. H. Zhang, A. Nanda, D. N. Granger. Platelet-Leukocyte-Endothelial Cell Interactions after Middle Cerebral Artery Occlusion and Reperfusion. J Cereb Blood Flow Metab 24: 907-15, 2004 http://dx.doi.org/10.1097/01.WCB.0000132690.96836.7F

J. Calvert, C. Zhou, J. Zhang. Exposure of Rat Pups to Hyperoxia at Normal and Hyperbaric Pressure does not Cause Retinopathy of Prematurity. Experimental Neurology 189: 150-161, 2004 http://dx.doi.org/10.1016/j.expneurol.2004.05.030

J. Tang, J. Liu, C. Zhou, J.S. Alexander, A. Nanda, D.N. Granger, J.H. Zhang. MMP-9 Deficiency Enhances Collagenase-induced Intracerebral Hemorrhage and Brain Injury in Transgenic Mice. J Cereb Blood Flow Metab 24: 1133-1145, 2004 http://dx.doi.org/10.1097/01.WCB.0000135593.05952.DE

S. Park, M. Yamaguchi, C. Zhou, J. Tang, J. Zhang. Neurovascular Protection Reduces Early Brain Injury after Subarachnoid Hemorrhage. Stroke 35: 2412-2417, 2004 http://dx.doi.org/10.1161/01.STR.0000141162.29864.e9

R. Wang, W. Shi, J. Sun, F. Wang, C. Liu, L. Zhou, B. Bin, J.H. Zhang. Caspase-3 Expression in Neuronal Cells induced by Oxyhemoglobin. Clinical Journal of Experimental Surgery 21: 888, 2004

M. Yamaguchi, C. Zhou, J. Zhang. Gene Transfer of EC-SOD Failed to Prevent Cerebral Vasospasm after Experimental Subarachnoid Hemorrhage. Stroke 35: 2512-2517, 2004 http://dx.doi.org/10.1161/01.STR.0000145198.07723.8e

Review

J.H. Zhang. Experimental Therapies for SAH and Cerebral Vasospasm (Review). Chinese Journal of Minimally Invasive Neurosurgery 9 (Suppl): 57-59, 2004

M. Ishikawa, J. Zhang, A. Nanda, D.N. Granger. Inflammatory Responses to Ischemia and Reperfusion in Cerebral Microcirculation (Review). Frontiers in Bioscience 9: 1339-1347, 2004 http://dx.doi.org/10.2741/1330

W. Yin, J. Zhang. Hyperbaric Oxygen Therapy for Cerebral Ischemia (Review). Research SignPost (Recent Res. Devel. Physiol.) 2: 247-257, 2004

Editorial

J.H. Zhang. Introduction to Special Issue: Apoptosis in Cerebral Ischemia. Neurological Research 26: 825-826, 2004

Journal Supplement

Y. Dai & J. Zhang. Chloride Efflux Involved in ET-1 and 5-HT Induced Contraction in Rabbit Basilar Artery. J Cardiovasc Pharmacol Supplement 44: Supplement 1: S125-128, 2004 http://dx.doi.org/10.1097/01.fjc.0000166225.96088.bd

A. Zubkov, L. Miao & J. Zhang. Signaling Pathways for ET-1 Induced Contraction in Rabbit Basilar Artery. J Cardiovasc Pharmacol Supplement 44: Supplement 1: S24-26, 2004

Book Chapter

J.H. Zhang. Experimental Therapy for SAH and Cerebral Vasospasm. Advances in Neurosciences-2004. Ed. X. Wang et al. Higher Education Press. Pp 635-645, 2004

H. Kimura, I. Gules, B. Chen, T. Meguro, A. Parent & J. Zhang. Cytokines Produce Apoptosis in Cultured Cerebral Endothelial. Cerebral Vasospasm (8th International Conference on Cerebral Vasospasm) Thieme, R.L. Macdonald. Pp 97-102, 2004

J. Zhang. Signaling Pathways in Cerebral Vasospasm. Cerebral Vasospasm (8th International Conference on Cerebral Vasospasm) Thieme, Ed. R.L. Macdonald. Pp 3-7, 2004

G. Kusaka, H. Kimura, I. Kusaka, E. Perkins, A. Nanda, J. Zhang. Inhibition of Src Tyrosine Kinase reduces Experimental Cerebral Vasospasm. Cerebral Vasospasm (8th International Conference on Cerebral Vasospasm) Thieme, R.L. Macdonald. Pp 17-19, 2004

D. Tyler, V. Overman, E. Flotte, J. Tyler, W. Johnson & J. Zhang. Sex and Racial Factors in the Outcome of Subarachnoid Hemorrhage in Mississippi . Cerebral Vasospasm (8th International Conference on Cerebral Vasospasm) Thieme, R.L. Macdonald. Pp 220-226, 2004

Y. Takanashi, T. Ishida, J.H. Zhang, I. Yamamoto. Prevention of Experimental Cerebral Vasospasm by Intrathecal Delivery of Liposomal Fasudil. Cerebral Vasospasm (8th International Conference on Cerebral Vasospasm) Thieme, R.L. Macdonald. Pp 153-155, 2004

S. Park, C. Zhou, J. Tang, A. Colohan, J.H. Zhang. Apoptosis, Neurovascular Protection, and Subarachnoid Hemorrhage. Pharmacology of Cerebral Ischemia. Ed. J. Krieglstein, S. Klumpp. 2004, p217-227

Book Review

J.H. Zhang, Book Review. “The Blood-Brain Barrier: Biology and Research Protocols” S. Nag ed. Totowa, New Jersey: Humana Press INC, 2003. Surgical Neurology 61: 409-410, 2004

J. Zhang. Book Review: Brain Edema XII: Proceedings of the 12th International Symposium. Kakone, Japan, November 10-13, 2002. (Acta Neurochirurgica Supplement 86. T. Kuroiwa, A. Baethmann, Z. Czemicki, J. Hoff, U. Ito, Y. Katayama, A. Marmarou, A.D. Mendelow, and H.J. Reulen, editors. New York: Springer-Verlag/Wein, 2003, 609 pp, illus. ISBN 3-211-00919-1. Price: $259.00.) J Neurosurg 101: 560-562, 2004

2003 

Original Article

J. Sung g, L. Miao, J. Calvert, L. Harkey & J. Zhang. Role of RhoA in Spinal Cord Injury. Brain Res 959: 29-38, 2003 http://dx.doi.org/10.1016/S0006-8993(02)03717-4

L. Richards, W.C. Lineaweaver, F. Stile, J. Zhang, F. Zhang. Effect of Hyperbaric Oxygen Therapy on the Tubed Pedicle Flap Survival in a Rat Model. Ann Plast Surg 50: 51-56, 2003 http://dx.doi.org/10.1097/00000637-200301000-00009

E. Perkins, J. Calvert, J. Lancom, A. Parent & J. Zhang. Inhibition of H-ras as a Treatment for Experimental C6 Glioma. Molecular Brain Res 111: 42-51, 2003 http://dx.doi.org/10.1016/S0169-328X(02)00668-X

G. Mandybur, Y. Miyagi, W. Yin, E. Perkins, A. Parent & J. Zhang. Cytotoxicity of Ventricular CSF from Parkinson Patients: Correlation with Clinical Profiles and Neurochemistry. Neurol Res 25: 104-111, 2003 http://dx.doi.org/10.1179/016164103101201021

A. Massey, L. Miao, B. Smith, J. Liu, I. Kusaka, J. Zhang & J. Tang. Increased RhoA Translocation in Renal Cortex of Diabetic Rats. Life Sci 27: 2943-2952, 2003 http://dx.doi.org/10.1016/S0024-3205(03)00228-5

G. Kusaka, H. Kimura, I. Kusaka, E. Perkins, A. Nanda, J. Zhang. Contribution of Src Tyrosine Kinase to Cerebral Vasospasm after Subarachnoid Hemorrhage. J Neurosurg 99: 383-390, 2003

M. Ishikawa, D. Cooper, J. Russell, J.W. Salter, J.H. Zhang, A. Nanda, D.N. Granger. Molecular Determinates of the Prothrombogenic and Inflammatory Phenotype Assumed by the Post Ischemic Cerebral Microcirculation. Stroke 34: 1777-1782, 2003 http://dx.doi.org/10.1161/01.STR.0000074921.17767.F2

D. Yin, C. Zhou, I. Kusaka, J. Calvert, A. Parent, A. Nanda & J. Zhang. Inhibition of Apoptosis by Hyperbaric Oxygen in a Rat Focal Cerebral Ischemic Model. J Cereb Blood Flow Metab 23: 855-864, 2003 http://dx.doi.org/10.1097/01.WCB.0000073946.29308.55

C. Zhou, Y. Li, A. Nanda, J. Zhang. HBO Suppresses Nogo-A, Ng-R, or RhoA Expression in Cerebral Cortex after Global Ischemia. Biochem Biophys Res Comm 309: 368-376, 2003 http://dx.doi.org/10.1016/j.bbrc.2003.08.006

J. Calvert, C. Zhou, A. Nanda, J. Zhang. Effect of HBO on Apoptosis in Neonatal Hypoxia Rat Model. J Applied Physiol 95: 2072-2080, 2003

H. Kimura, I. Gules, T. Meguro & J. Zhang. Cytotoxicity of Cytokines in Cerebral Microvascular Endothelial Cell. Brain Res 990: 148-156, 2003 http://dx.doi.org/10.1016/S0006-8993(03)03450-4

Review

J. Zhang, H. Kimura, A. Nanda. New Frontier in Cerebral Vasospasm: Signaling Pathway. Advances in Brain Research -Cerebrovascular Disorders and Neurodegeneration. Excerpta Medica International Congress Series 1251, Neurology, Elsevier Science pp3-15, 2003

A. Zubkov, A. Nanda & J. Zhang. Signal Transduction in Cerebral Vasospasm (Review). Pathophysiology 9: 47-61, 2003 http://dx.doi.org/10.1016/S0928-4680(02)00055-X

Editorial Letter

J. Zhang, A. B. Singhal, J. Toole. Oxygen Therapy in Ischemic Stroke. Letter to the Editor. Stroke 34: E152-153, 2003 http://dx.doi.org/10.1161/01.STR.0000087098.30644.E1

Journal Supplement

L. Huang, M. Mehta, A. Nanda & J. Zhang. The Role of Multiple Hyperbaric Oxygenation in Expanding Therapeutic Windows after Acute Spinal Cord Injury in Rats. J Neurosurg 99 (2 Suppl): 198-205, 2003

L. Huang, M. Mehta, J. Eichhorn, A. Nanda & J. Zhang. Multiple Hyperbaric Oxygenation (HBO) Expands the Therapeutic Window in Acute Spinal Cord Injury in Rats. Acta Neurochir Suppl 86: 433-438, 2003

M. Sato, J. Tang, A. Nanda & J. Zhang. Heat Shock Proteins Expression in Brain Stem after Subarachnoid Hemorrhage in Rats. Acta Neurochir Suppl 86: 477-482, 2003

I. Gules, M. Sato, A. Nanda & J. Zhang. Apoptosis, Blood-Brain Barrier, Subarachnoid Hemorrhage. Acta Neurochir Suppl 86: 483-487, 2003

2002

Original Article

W. Yin, A. Badr, G. Mychaskiw & J. Zhang. HBO Reduces COX-2 Expression and Infarction in MCAO Rats. Brain Res 926: 165-171, 2002

H. Kimura, K. Sasaki, T. Meguro & J. Zhang. Phosphatidylinositol 3-Kinase Inhibitor Failed to Reduce Cerebral Vasospasm in Dog Model of Experimental Subarachnoid Hemorrhage. Stroke 33: 593-599, 2002 http://dx.doi.org/10.1161/hs0202.103398

M. Sato, A. Parent & J. Zhang. Inhibitory Effect with Antisense Mitogen-activated Protein Kinase Oligodeoxynucleotide against Cerebral Vasospasm in Rats. Stroke 33: 775-781, 2002 http://dx.doi.org/10.1161/hs0302.103734

Y. Dai & J. Zhang. Manipulation of Chloride Flux affects Histamine-induced Contraction in Rabbit Basilar Artery. Am J Physiol Heart Circ Physiol 282: H1427-36, 2002

E. Akin, B. Clower, R. Tibbs, J. Tang & J. Zhang. Bilirubin Induces Apoptosis in Cultured Brain Endothelial Cells. Brain Res 931: 168-175, 2002 http://dx.doi.org/10.1016/S0006-8993(02)02276-X

K. Aoki, A. Zubkov, R. Tibbs & J. Zhang. Role of MAPK in Chronic Cerebral Vasospasm. Life Sci 70: 1901-1908, 2002 http://dx.doi.org/10.1016/S0024-3205(02)01499-6

A. Zubkov, S. Rollins & J. Zhang. KCl-induced MAPK Activation and Contraction in Rabbit Basilar Artery. Biochem Biophys Res Commun 293: 660-664, 2002

AY. Zubkov, R. Tibbs, B. Clower, K. Ogihara, K. Aoki & J.H. Zhang. Morphological Changes of Cerebral Arteries in a Canine Double Hemorrhage Model. Neurosci Lett 326: 137-141, 2002 http://dx.doi.org/10.1016/S0304-3940(02)00188-X

H. Kimura, T. Meguro, A. Badr & J. Zhang. Suramin-induced Reversal of Chronic Cerebral Vasospasm in Experimental Subarachnoid Hemorrhage. J Neurosurg 97: 129-135, 2002

M. Sato, E. Perkins, H. Kimura, C. Yi, D. Heistat, J. Tang & J. Zhang. Posttreatment with Adenovirus-mediated Gene Transfer of Calcitonin Gene-related Peptide to Reverse Cerebral Vasospasm in Dogs. J Neurosurg 97: 136-142, 2002

A. Zubkov, K. Aoki, A. D. Parent & J. Zhang. Preliminary Study of the Effect of Caspase Inhibitors on Vasospasm in Dog Penetrating Arteries. Life Sci 70: 3007-3018, 2002 http://dx.doi.org/10.1016/S0024-3205(02)01550-3

L. Miao, J. Calvert, J. Tang & J. Zhang. Upregulation of Small GTPase RhoA in the Basilar Artery from Diabetic (mellitus) Rat. Life Sci 71: 1175-1185, 2002 http://dx.doi.org/10.1016/S0024-3205(02)01827-1

S. Rollins, E. Perkins, G. Mandybur & J. Zhang. OxyHb Prevents Growth of Astrocytes. Brain Res 945: 41-49, 2002
L. Miao, Y. Dai & J. Zhang. Mechanisms of RhoA/ROK kinase Activation in Endothelin-1-induced Contraction in Rabbit Basilar Artery. Am J Physiol Heart Circ Physiol 283(3):H983-9, 2002

W. Yin, R. Tibbs, J. Tang, A. Badr & J. Zhang. Role of Hemoglobin and ATP in Cerebral Vasosapsm. J Clin Neurosci 9:425-428, 2002

J.W. Calvert, W. Yin, M. Patel, A. Badr, G. Mychaskiw, A. Parent & J. Zhang. Hyperbaric Oxygenation Prevented Brain Injury induced by Hypoxia-Ischemia in a Neonatal Rat Model. Brain Res 951: 1-8, 2002 http://dx.doi.org/10.1016/S0006-8993(02)03094-9

E. Perkins, H. Kimura, A. Parent & J. Zhang. Evaluation of the Micro-vasculature and Cerebral Ischemia after Experimental Subarachnoid Hemorrhage in Dogs. J Neurosurg 97: 896-904, 2002

I. Gules, M. Sato, B. Clower, A. Nanda & J. Zhang. Comparison of Three Rat Models of Cerebral Vasospasm. Am J Physiol Heart & Circ Physiol 283: H2551-2559, 2002

K. Aoki, A. Zubkov, I. Ross & J. Zhang. Therapeutic Effect of Caspase Inhibitors in the Prevention of Apoptosis and Reversal of Chronic Cerebral Vasospasm. J Clin Neurosci 9: 672-677, 2002 http://dx.doi.org/10.1054/jocn.2002.1088

Journal Supplement

Yin W, Tibbs R, Aoki K, Badr A, Zhang J. Metabolic Alterations in Cerebrospinal Fluid from Double Hemorrhage Model of Dogs. Acta Neurochir Suppl 81:257-63, 2002

Book Chapter

J. Zhang, M. Satoh, D. Heistad, A. Nanda. Signal Transduction and Gene Therapy for Cerebral Vasospasm. Pharmacology of Cerebral Ischemia. Ed. J. Krieglstein, S. Klumpp. Pp 141-150, 2002

2001

Original Article

A. Zubkov, S. Rollins, A. Parent & J. Zhang. Relaxant Effect of U0126 in Hemolysate-, Oxyhemoglobin- and Bloody Cerebrospinal fluid-induced Contraction in Rabbit Basilar Artery. Stroke 32: 154-161, 2001

T. Meguro, B. Chen, A. Parent & J. Zhang. Caspase II and III Inhibitors Prevent Oxyhemoglobin-Induced Apoptotic Changes in Endothelial Cells. Stroke 32: 561-566, 2001

W. Yin, R. Tibbs, A. Badr & J. Zhang. Metabolic Alterations in CSF from Double Hemorrhage Model of Dogs. Neurol Res 23: 87-92, 2001 http://dx.doi.org/10.1179/016164101101198181

R. Carpenter, L. Miao, Y, Miyagi, E. Bengten & J. Zhang. Altered Expression of P(2) Receptor mRNAs in the Basilar Artery in a Rat Double Hemorrhage Model. Stroke 32: 516-522, 2001

A. Badr, W. Yin, G. Mychaskiw & J. Zhang. Dual Effect of Hyperbaric Oxygen on Cerebral Infarction in Rat MCA Occlusion Model. Am J Physiol Regul Integr Comp Physiol 280: R766-R770, 2001

K. Ogihara, K. Aoki, A. Zubkov & J. Zhang. Oxyhemoglobin Produces Apoptosis and Necrosis in Cultured Smooth Muscle Cells. Brain Res 889 (1-2): 89-97, 2001 http://dx.doi.org/10.1016/S0006-8993(00)03120-6

T. Meguro, B. Chen, J. Lancon & J. Zhang. OxyHb Induces Caspase-Mediated Cell Death in Cerebral Endothelial Cells. J Neurochem 77: 1128-1135, 2001 http://dx.doi.org/10.1046/j.1471-4159.2001.00313.x

Y. Takanashi, T. Ishida, T. Meguro, H. Kiwada, J. Zhang & I. Yamamoto. Efficacy of Intrathecal Liposome Fasudil for Experimental Cerebral Vasospasm following Subarachnoid Hemorrhage in Dogs. Neurosurgery 48: 894-901, 2001 http://dx.doi.org/10.1097/00006123-200104000-00041

K. Aoki. R. Williams & J. Zhang. Mechanism of Hemolysate-Induced [Ca 2+]i Elevation in Cultured Human Fibroblasts. Neurol Res 23: 367-373, 2001 http://dx.doi.org/10.1179/016164101101198578

T. Meguro, B. Clower, R. Carpenter, A. Parent & J. Zhang. Improved Rat Model in Cerebral Vasospasm Studies. Neurol Res 23: 761-766, 2001 http://dx.doi.org/10.1179/016164101101199144

L. Miao, J. Calvert, J. Tang, A. Parent & J. Zhang. Age-related Rho -A Expression in Blood Vessels of Rats. Mech Ageing Dev 122: 1757-1770, 2001 http://dx.doi.org/10.1016/S0047-6374(01)00297-4

A. Badr, W. Yin, G. Mychaskiw & J. Zhang. Effect of Hyperbaric Oxygen on Striatal Metabolites: A Microdialysis Study in Awaken Freely Moving Rats after MCA Occlusion. Brain Res 916: 85-90, 2001 http://dx.doi.org/10.1016/S0006-8993(01)02867-0

Y. Dai, J. Zhang. Role of Chloride Channels in Endothelin-1 Induced Contraction in Rabbit Basilar Artery. Am J Physiol Heart Circ Physiol 281: H2159-2167, 2001

Y. Takanashi, T. Ishida, T. Meguro, M.J. Kirchmeier, T.M. Allen, J.H. Zhang. Intrathecal Application with Liposome-entrapped Fasudil for Cerebral Vasospasm following Subarachnoid Hemorrhage in Rats. J Clin Neuroscience 8: 557-561, 2001 http://dx.doi.org/10.1054/jocn.2001.0998

L. Miao, J. Tang, D. Esposito & J. Zhang. Age-related Changes of P 2 Receptor mRNAs of Rat Cerebral Arteries. Experimental Gerontology 37: 67-79, 2001 http://dx.doi.org/10.1016/S0531-5565(01)00159-0

Review

I. Laher & J. Zhang. Protein Kinase C and Cerebral Vasospasm (Review). J Cereb Blood Flow Metab 21: 887-906, 2001
J. Zhang. The Role of MAPK in Cerebral Vasospasm (Review). Drug News & Perspectives 14(5): 261-267, 2001

Editorial

J. Zhang. Editorial: A New Era in Stroke Research. Journal of Stroke 1: 4, 2001

Journal Supplement

Y. Takanashi, T. Ishida, T. Meguro, M. Kirchmeier, T. Allen, J. Zhang. A Novel Drug Delivery System as Prophylaxis for Cerebral Vasospasm. Acta Neurochirugica (Suppl) 77 (44): 213-216, 2001

K. Aoki, A. Zubkov, R. Tibbs, T. Meguro, J. Zhang. Role of MAPK in Chronic Cerebral Vasospasm. Acta Neurochirugica (Suppl) 77 (44): 55-58, 2001

A. Zubkov, K. Rollins, B. McGehee, A. Parent, J. Zhang. Role of Mitogen-activated Protein Kinase in the Contractions of Rabbit Basilar Artery induced by Hemolysate, Oxyhemoglobin, and Bloody CSF. Acta Neurochirugica (Suppl) 77 (44): 25-28, 2001

A. Zubkov, R. Tibbs, B. Clower, K. Ogihara, K. Aoki, J. Zhang. Apoptosis in Basilar Endothelial Cells in a Canine Double Hemorrhage Model. Acta Neurochirugica (Suppl) 77 (44): 29-32, 2001

Book Chapter

H. Kimura, R. Carpenter, A. Parent, J. Zhang. Role of ATP/P2 Receptors in Cerebral Vasospasm. Proceedings of the 7th World congress for Microcirculation. Sidney, Australia, August 19-23, 2001

2000

Editor for Special Journal Issue

J.H. Zhang: On-line Proceedings of Stroke/Cerebral Vascular Physiology Symposium of the 6th Internet World Congress on Biomedical Sciences 2000 at Hospital of Ciudad Real, Diudad Real, Spain

Original Article

A. Zubkov, S. Rollines, A. Parent & J. Zhang. Mechanism of Endothelin-1 Induced Contraction in Rabbit Basilar Artery. Stroke 31: 526-533, 2000

K. Aoki, A. Parent & J. Zhang. Damnacanthal Releases Ca 2+ from Internal Stores and Promotes Ca 2+ Entry in Rat Basilar Smooth Muscle Cells. Eur J Pharmacol 387: 119-124, 2000

A. Zubkov, A. Lewis, F. Raila, J. Zhang & A. Parent. Risk Factors for the Development of Posttraumatic Vasospasm. Surg Neurol 53: 126-130, 2000

K. Ogihara, A.Y. Zubkov, D.H. Bernanke, A.D. Parent & J. Zhang. The Effects of Endothelin Receptor Antagonists on Non-Muscle Matrix Compaction in a Cell Culture Vasospasm Model. Neurol Res 22: 209-214, 2000

A.Y. Zubkov, K. Ogihara, A. Parent & J. Zhang. Apoptosis of Endothelial Cells in Vessel Affected by Cerebral Vasospasm. Surgical Neurol 53: 260-266, 2000

A. Patlolla, A. Zubkov, A. Parent & J. Zhang. Hemolysate Activate p21Ras in Rabbit Basilar Artery. Life Sci 67: 1233-1242, 2000

K. Aoki. A. Zubkov, A. Parent & J. Zhang. Mechanism of ATP-Induced [Ca 2+ ] i mobilization in Rat Basilar Smooth Muscle Cells. Stroke 31: 1377-1385, 2000

Y. Miyagi, R. Carpenter, T. Meguro, A. Parent & J. Zhang. Up-regulation of Rho -A and Rho-Kinases in Rat Double Hemorrhage Model. J Neurosurg 93: 471-476, 2000

T. Meguro, C. Klett, B. Chen, A. Parent, & J. Zhang. Role of Ca 2+ Channels in Oxyhemoglobin-Induced Apoptosis in Endothelial Cells. J Neurosurg 93: 650-656, 2000

G. Mychaskiw, A. Badr, R. Tibbs, B. Clower & J. Zhang. Optison (FS069) Disrupts the Blood-Brain Barrier in Rats. Anesthesia and Analgesia 91: 798-803, 2000

R. Tibbs, A. Zubkov, K. Aoki, T. Meguro, A. Badr, A. Parent & J. Zhang. Effects of Mitogen-Activated Protein Kinase Inhibitors on Cerebral Vasospasm in a Double-Hemorrhage Model in Dogs. J Neurosurg 93: 1041-1047, 2000

A. Zubkov, R. Tibbis, K. Aoki & J. Zhang. Morphological Changes in Cerebral Penetrating Arteries in a Canine Double Hemorrahge Model. Surg Neurol 54: 212-220, 2000

A. Zubkov, R. Tibbs, K. Aoki & J. Zhang. Prevention of Vasospasm in Penetrating Arteries with MAPK Inhibitors in a Dog Double-Hemorrhage Model. Surg Neurol 54: 221-228, 2000

J. Tang & J. Zhang. Mechanism of Ca 2+ Elevation by H 2 O 2 in Islets of Rats. Life Sci 68: 475-481, 2000

Review

J. Zhang. Protein Kinase C and Cerebral Vasospasm: Past and Future (Review). Neurol Res 22: 369-378, 2000

Editorial Letter

J. Zhang. Oxyhemoglobin and Apoptosis. Letter to the Editor. J Neurosurg 92: 899-902, 2000

J. Zhang. Oxyhemoglobin and Intracellular Calcium. Letter to the Editor. J Neurosurg 93: 370-371, 2000

Journal Supplement

K. Ogihara, A. Zubkov, A. Parent & J. Zhang. Oxyhemoglobin Produces Necrosis in Cultured Smooth Muscle Cells. Acta Neurochirurgica (suppl) 76: 507-510, 2000

A. Patlolla, K. Ogihara, A. Zubkov, K. Aoki, A. Parent & J. Zhang. Role of Tyrosine Kinase in Fibroblast Compaction and Cerebral Vasospasm. Acta Neurochirurgica (suppl) 76: 227-230, 2000

A.Y. Zubkov, A. Pilkington, A.D. Parent & J.H. Zhang. Morphological Presentation of Posttraumatic Vasospasm. Acta Neurochirurgica (suppl) 76: 223-226, 2000

A. Zubkov, K. Ogihara, A. Patlolla, A. Parent & J. Zhang. Mitogen-Activated Protein Kinase Plays an Important Role in Hemolysate-Induced Contraction in Rabbit Basilar Artery. Acta Neurochirurgica (suppl) 76: 217-221, 2000

Book Chapter

K. Ogihara, A. Zubkov, R. Tibbs, A. Parent & J. Zhang. Role of Apoptosis in Cerebral Vasospasm after Subarachnoid Hemorrhage. Ed Y. Fukuuchi, M. Tomita. Ischemic Blood Flow in the Brain. Springer, 2000, pp 202-208

J. Zhang. Protein Kinase C Net Work in Cerebral Vasospasm. Ed. M. Garcia-Rojo. On-line Proceedings of the 6 th Internet World Congress on Biomedical Sciences'2000 at Hospital of Ciudad Real, Diudad Real, Spain .

R. Tibbs, J. Tang & J. Zhang. Bilirubin Produces Apoptosis in Cultured Endothelial Cells. Ed. M. Garcia-Rojo. On-line Proceedings of the 6 th Internet World Congress on Biomedical Sciences'2000 at Hospital of Ciudad Real, Diudad Real, Spain .

A. Zubkov, R. Tibbs & J. Zhang. Morphological Changes in Cerebral Penetrating Arteries during Vasospasm. Ed. M. Garcia-Rojo. On-line Proceedings of the 6 th Internet World Congress on Biomedical Sciences'2000 at Hospital of Ciudad Real, Diudad Real, Spain

T. Meguro, C. Klett & J. Zhang. Role of Calcium Channels in OxyHb-induced Apoptosis in Endothelial Cells. Ed. M. Garcia-Rojo. On-line Proceedings of the 6th Internet World Congress on Biomedical Sciences'2000 at Hospital of Ciudad Real, Diudad Real, Spain

J. Zhang. Stroke/Cerebral Vascular Physiology. Conference Proceedings of the 6 th Internet World Congress for Biomedical Sciences. Ed. M. Garcia-Rojo. June 2000. Pp12-13

A. Zubkov & J. Zhang. Cerebral Vasospasm of Penetrating Arteries in Brain Stem. Pharmacology of Cerebral Ischemia. Ed. J. Krieglstein, S. Klumpp. 2000, Pp307-316

1999

Original Article

R.L. Macdanold, J. Zhang, L. Marton & B. Weir. Effects of Cell-Permeant Calcium Chelators on Contractility in Monkey Basilar Artery. J Neurotrauma 16: 37-47, 1999

J.R. Brorson, P.T. Schumacker & H. Zhang. Nitric Oxide Acutely Inhibits Neuronal Energy Production. J Neuroscience 19: 147-158, 1999

S. Iwabuchi, L.S. Marton & J. Zhang. Tyrosine Kinase Mediated The Effect of Hemolysate on [Ca2+]i in Rat Basilar Smooth Muscle Cells. J Neurosurg 90: 127-135, 1999

A. Zubkov, K. Ogihara, P. Tumu, A. Patlolla, A. Lewis, A. Parent & J. Zhang. Mitogen-Activated Protein Kinase Mediates Hemolysate-Induced Contraction of Rabbit Basilar Artery. J Neurosurg 90: 1091-1097, 1999

A.Y. Zubkov, K. Ogihara, P. Tumu, G. Mandybur, A. Lewis, A. Parent & J. Zhang. Bloody Cerebrospinal Fluid Alters Contractility of Cultured Arteries. Neurol Res 21: 553-558, 1999

C.J. Kim, K.W. Kim & J. Zhang. Role of KCa in Hemolysate-Induced Contraction of Rabbit Basilar Artery. Neurol Res 21: 705-711, 1999

K. Ogihara, A. Zubkov, D.H. Bernanke, A. Lewis, A. Parent & J. Zhang. Oxyhemoglobin Produced Apoptosis in Cultured Endothelial Cells. J Neurosurg 91: 459-465, 1999

A. Zubkov, A.S. Pilkington, D. Bernanke, A.D. Parent & J. Zhang & A. Parent. Posttraumatic Cerebral Vasospasm: Clinical and Morphological Presentations. J Neurotrauma 16: 763-770, 1999

A. Patlolla, K. Ogihara, K. Aoki, A. Zubkov, E. Bengten, A. Parent & J. Zhang. Hemolysate Induced Tyrosine Phosphorylation and Collagen-Lattice Compaction in Cultured Fibroblasts. Biochem Biophys Res Comm 264: 100-107, 1999

Editorial

M. Boegehold, R.M.K.W. Lee, M.J. Mulvany, B. Nilius, R.L. Prewitt & J. Zhang. Vascular Research at INABIS 98. J Vasc Res (Blood Vessels) 36: 147-150, 1999

Book Chapter

B. Sima, B. Weir, RL. Macdonald & H. Zhang. P2u Receptors Mediated The Effect of Hemolysate on [Ca2+]I in Rat Basilar Smooth Muscle Cells. Ed N.W.C. Dorsch. Cerebral Vasospasm VI. Oslington Consulting Pty Ltd. 40-42, 1999

C.J. Kim, K.W. Kim, J.W. Park, J.C. Lee & H. Zhang. Role of Tyrosine Phosphorylation in Hemolysate-induced Contraction in Rabbit Basilar Artery. Ed N.W.C. Dorsch. Cerebral Vasospasm VI. Oslington Consulting Pty Ltd. 43-44, 1999

C.J. Kim, J.C. Lee & H. Zhang. Hemolysate Modulates Cerebral Vascular Smooth Muscle Potassium and Calcium Channels. Ed N.W.C. Dorsch. Cerebral Vasospasm VI. Oslington Consulting Pty Ltd. 31-32,1999

R.L. Macdonald, J. Zhang & A. Hino. Characterization of Endothelin Receptors in Monkey Basilar Artery. Ed N.W.C. Dorsch. Cerebral Vasospasm VI. Oslington Consulting Pty Ltd. 2-6, 1999

R.L. Macdonald, B. Weir, J. Zhang, L. Marton, M Sajdak & L. Johns. Adenosine Triphosphate as A Possible Cause of Vasospasm In Monkeys. Ed N.W.C. Dorsch. Cerebral Vasospasm VI. Oslington Consulting Pty Ltd. 58-62, 1999

1998

Editor for Special Journal Issue

J.H. Zhang: On-line Proceedings of Stroke/Cerebral Vasospasm Symposium of the 5th Internet World Congress on Biomedical Sciences'98 at McMaster University, Canada, 1998

Original Article

C.J. Kim, B. Weir, R.L. Macdonald & H. Zhang. Hemolysate Releases Ca2+ from IP3 Receptors and Activates Ca2+-Dependent K+ Channels in Rat Basilar Smooth Muscle Cells. Neurol Res 20: 23-30, 1998

R.L. Macdonald, J. Zhang, B. Weir, L. Marton & R. Wollman. Adenosine Triphosphate Causes Vasospasm of the Rat Femoral Artery. Neurosurgery 42: 825-833, 1998

C.J. Kim, K.W. Kim, J.W. Park, J.C. Lee & J. Zhang. Role of Tyrosine Kinase in Erythrocyte Lysate-Induced Contraction of Rabbit Cerebral Arteries. J Neurosurg 89: 289-296, 1998

Y. Guan, B. Weir, L.S. Marton, R.L. Macdonald & H. Zhang. Comparison of the Effects of Hemolysate at Different Ages on [Ca2+]i in Rat Basilar Arterial Cells. J Neurosurg 89: 1007-1014, 1998

Review

H. Zhang, A. Lewis, D. Bernanke, A. Zubkov & B. Clower. Stroke - Anatomy of A Catastrophic Event (Review). Anat Rec (New Anat) 253: 58-63, 1998

Book Chapter

H. Zhang, B. Sima, RL Macdonald & B. Weir. P2 Receptors in Cerebral Arteries. Ed H. Szechtman. On-line Proceedings of the 5th Internet World Congress on Biomedical Sciences'98 at McMaster University, Canada.

J. Zhang, K. Ogihara, D. Bernanke, A. Lewis & A. Parent. Oxyhemoglobin Produced Apoptosis in Cultured Endothelial. Ed H. Szechtman. On-line Proceedings of the 5th Internet World Congress on Biomedical Sciences'98 at McMaster University, Canada.

A.Y. Zubkov, K. Ogihara, P. Tumu, A.I. Lewis, A.D. Parent, J. Zhang. Mitogen-Activated Protein Kinase is involved In the Pathogenesis of Cerebral Vasospasm. Ed H. Szechtman. On-line Proceedings of the 5th Internet World Congress on Biomedical Sciences'98 at McMaster University, Canada.

S. Iwabuchi, J. Zhang, L. Marton etc. Tyrosine Kinase and Cerebral Vasospasm. Ed H. Szechtman. On-line Proceedings of the 5th Internet World Congress on Biomedical Sciences'98 at McMaster University, Canada.

R.L. Macdonald, J. Zhang, L. Marton, B. Weir etc. Spasmogens in Cerebral Vasospasm. Ed H. Szechtman. On-line Proceedings of the 5th Internet World Congress on Biomedical Sciences'98 at McMaster University, Canada.

1997

Original Article

J. Brorson, R.A. Sulit & H. Zhang. Nitric Oxide Disrupts Ca2+ Homeostasis in Hippocampal Neurons. J Neurochem 68: 95-105, 1997

J. Kane, R.L. Macdanold, J. Zhang & B. Sima. HEPES Inhibits Contractile Responses of Canine Basilar Artery. Neurol Res 19: 527-533, 1997

H. Zhang, B. Weir, L. Marton, K. Lee & L. Macdonald. P2 Purinoceptors in Bovine Middle Cerebral Artery Endothelial Cells. J Cardiovsc Pharmacol 30: 767-774, 1997

B. Sima, B. Weir, R.L. Macdonald & H. Zhang. Extracellular Nucleotide-Induced [Ca2+]i Elevation in Rat Basilar Smooth Muscle Cells. Stroke 28: 2053-2059, 1997

J. Brorson & H. Zhang. Disrupted [Ca2+]i Homeostasis Contributes to the Toxicity of Nitric Oxide in Cultured Hippocampal Neurons. J Neurochem 69: 1882-1889, 1997

R.L. Macdonald, B. Weir, J. Zhang, L.S. Marton, M. Sajdak, L.M. Johns. Adenosine Triphosphate and Hemoglobin in Vasospastic Monkeys. J Neurosurg (Neurosurg Focus) 3: article 3, 1-7, 1997

1996

Original Article

J. Tang, W. Pugh, K. Polonsky & H. Zhang. Preservation of Insulin Secretary Responses to P2-Purinoceptor Agonists in Zucker Diabetic Fatty Rats. Am J Physiol Endocri Physiol 270: E504-512, 1996

C.J. Kim, B. Weir, R.L. Macdonald, L.S. Marton & H. Zhang. Hemolysate Inhibits L-Type Ca2+ Channels in Rat Basilar Smooth Muscle Cells. J Vascular Res (Blood Vessels) 33: 258-264, 1996

H. Zhang, B. Sima, L.M. Johns & R.L. Macdonald. Time Course of Changes in Arterial Relaxation Following Subarachnoid Hemorrhage in Dogs. Neurol Res 18: 227-232, 1996

H. Zhang, B. Weir, R.L. Macdonald & L. Marton. Mechanisms of [Ca2+]i Elevation Induced by Erythrocyte Components in Endothelial Cells. J Pharmacol Exp Ther 277: 1501-1509, 1996

L.S. Marton, B. Weir & H. Zhang. Tyrosine Phosphorylation And [Ca2+]i Elevation Induced by Hemolysate in Bovine Endothelial Cells: Implication for Cerebral Vasospasm. Neurol Res 18: 349-353, 1996

B. Sima, R.L. Macdanold, B. Weir, L. Marton & H. Zhang. Effect of P2-Purinoceptor Antagonists on Hemolysate- and ATP-Induced Contractions of Dog Basilar Artery in Vitro. Neurosurgery 39: 815-822, 1996

Book Chapter

R.L. Macdonald, X. Wang, J. Zhang & L. Marton. Molecular Changes with Subarachnoid Hemorrhage and Vasospasm. Ed. C. Raffel, G. Harsh. The Molecular Biology of Neurosurgical Disease. Concepts in Neurosurgery, Vol. 8. Williams & Wilkins, Baltimore, 1996, chapter 17, pp278-293

1995

Original Article

M. Inazu, H. Zhang & E. Daniel. Different Mechanisms Can Activate Ca2+ Entrance via Cation Currents In Endothelial Cells. Life Sci 56: 11-17, 1995

H. Zhang, B. Weir & E. Daniel. Activation of Protein Kinase C Inhibits Potassium Currents. Pharmacology 50: 247-256, 1995

R.L. Macdonald, J. Zhang & H. Han. Pharmacological Study of Effect of Angioplasty on Rabbit Carotid Arteries with and Without Vasospasm. Stroke 26: 1053-1059, 1995

R.L. Macdonald, J. Zhang, B. Sima & L. Johns. Papaverine-sensitive Vasospasm and Arterial Contractility and Compliance Following Subarachnoid Hemorrhage in Dogs. Neurosurgery 37: 962-968, 1995

H. Zhang, B. Weir, L. Marton, R.L. Macdonald, V. Bindokas, R. Miller & J. Brorson. Mechanisms of Hemolysate-Induced Calcium Elevation in Cerebral Smooth Muscle Cells. Am J Physiol Heart Circulatory Physiol 269: H1874-1890, 1995

1994

Original Article

H. Zhang, M. Inazu, B. Weir, M. Buchanan & E. Daniel. Cyclopiazonic Acid Stimulates Calcium Influx through Non-Specific Cation Channels In Endothelial Cells. Eur J Pharmacol 251: 119-125, 1994

H. Zhang, M. Inazu, B. Weir & E. Daniel. Endothelin-1 Inhibits Inward Rectifier Potassium Channel and Activates Non-Specific Cation Channel in Cultured Endothelial Cells. Pharmacology 49: 11-22, 1994

M. Inazu, H. Zhang & E. Daniel. Properties of the LP-805-induced Potassium Currents in Cultured Bovine Pulmonary Endothelial Cells. J Pharmacol Exp Ther 268: 403-408, 1994

H. Zhang & D. Cook. Antagonism of Eicosanoid-Induced Contraction of Rat Aorta by Sulphonylureas. Pharmacology 49: 173-183, 1994

Review

H. Zhang & D. Cook. Cerebral Vascular Smooth Muscle Potassium Channels and Their Possible Role in the Management of Cerebral Vasospasm (Review). Pharmacol & Toxicol 75: 327-336, 1994

1993

Original Article

M. Inazu, H. Zhang & E. Daniel. LP-805, A Releaser of Endothelium-Derived Nitric Oxide, Activates an Endothelial Calcium Permeable Non-Specific Cation Channel. Life Sci 53: PL 315-320, 1993

Y. Guan, J. Zhang, R. Lee, C. Kwan & E. Daniel. Cyclopiazonic Acid Enhanced the Ca2+-Dependent Outward K+ Currents in Cultural Aortic Smooth Muscle Cells from SHR and WKY. Chinese Pharmacol Bull 9: 257-260, 1993

Book Chapter

H. Zhang, M. Inazu, E. Daniel & B. Weir. Cyclopiazonic Acid Releases Nitric Oxide from Endothelium by Stimulate Calcium Influx through Nonselective Cation Channels. Ed. J.M. Findlay. Developments in Neurology 8: Cerebral Vasospasm. Elsevier Science Publisher B.V. 225-228, 1993

H. Zhang, M. Inazu, E. Daniel & B. Weir. Activation of Protein Kinase C Inhibits Potassium Channels in Cultured Endothelial Cells. Ed. J.M. Findlay. Developments in Neurology 8: Cerebral Vasospasm. Elsevier Science Publisher B.V. 133-136, 1993

M. Inazu, H. Zhang, E. Daniel & B. Weir. Effects of LP-805, A Releaser of Endothelium-Derived Nitric Oxide, On Ion Channels in Cultured Endothelial Cells. Ed.J.M. Findlay. Developments in Neurology 8: Cerebral Vasospasm. Elsevier Science Publisher B.V. 243-246, 1993

1992

Original Article

H. Zhang, B. Weir, N. Stockbridge, M. Doi & D. Cook. Glibenclamide Inhibits the Contractile Responses of Canine Middle Cerebral Artery To Eicosanoids And Oxyhemoglobin. Cerebrovasc Dis 2: 51-57, 1992

H. Zhang, N. Stockbridge, B. Weir, B. Vollrath & D. Cook. Vasodilatation of Canine Cerebral Arteries by Nicorandil, Pinacidil and Lemakalim. Gen Pharmacol 23: 197-201, 1992

N. Stockbridge, H. Zhang & B. Weir. Potassium Currents of Rat Basilar Artery Smooth Muscle Cells. Pflügers Arch 420: 37-42, 1992

H. Zhang, B. Weir, M. Doi, H. Kasuya & D. Cook. Relaxant Effects of Iloprost in Canine Cerebral Artery. Can J Physiol Pharmacol 70: 712-716, 1992

1991

Original Article

H. Zhang, N. Stockbridge, B. Weir, C. Krueger & D. Cook. Glibenclamide Relaxes Vascular Smooth Muscle Constriction Produced by Prostaglandin F2a. Eur J Pharmacol 195: 27-35, 1991

N. Stockbridge, H. Zhang & B. Weir. Effects of K+ Channel Agonists Cromakalim and Pinacidil On Rat Basilar Artery Smooth Muscle Cells Are Mediated By Ca++-Activated K+ Channels. Biochem Biophys Res Commun 181: 172-178, 1991

Book Chapter

H. Zhang, N. Stockbridge & B. Weir. Effects of Pinacidil, Cromakalim and Nicorandil on Potassium Currents of Rat Basilar Artery Smooth Muscle. Adv Exp Med Biol 304: 531-541, 1991