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Am I At Risk for Uterine Sarcoma?

There is really no way to know for sure if you’re going to get uterine sarcoma. Still, certain factors can make you more likely to get uterine sarcoma than another woman. These are your risk factors. However, just because you have one or more risk factors does not necessarily mean you will get uterine sarcoma. In fact, you can have all the risk factors and still not get uterine sarcoma. Or you can have no known risk factors and get it.

If you agree with any of the following bolded statements, you are at an increased risk for uterine sarcoma.

I have been treated with radiation in the pelvic area for other cancers.

This increases your risk for uterine sarcoma. Radiation damages even healthy cells, which may make cancer develop easier. When cancers do occur because of this exposure, it is usually five to 25 years after the treatment.

I am African-American.

For reasons not understood, African-American women are two times more likely to develop uterine sarcoma than white or Asian women. Whether this tendency is due to an inherited risk or some other factor is not yet known.

I have taken or am taking tamoxifen. 

Women who take tamoxifen to prevent or treat breast cancer are more likely to have uterine sarcoma than those who don't take this medication. This may be due to the effects of estrogen on the uterus.  

Is uterine sarcoma hereditary?

Doctors do not know all the risk factors for uterine sarcoma. So they don’t really know if it is hereditary.