What is cancer of the penis?
Men who are not
A doctor should be seen if there are any of the following problems: growths or sores on the penis, any unusual liquid coming from the penis (
If there are
Stages of cancer of the penis
connective tissuejust under the skin of the penisand to one lymph nodein the groin; or
tissue(spongy tissue that gets larger to make an erection) and may have spread to one lymph node in the groin.
connective tissueor erectile tissueof the penisand to more than one lymph nodein the groin; or
urethraor prostate, and may have spread to one or more lymph nodes in the groin.
tissuesnext to the penisand may have spread to lymph nodesin the groinor pelvis; or
anywhere in or near the penis and in one or more lymph nodes deep in the pelvis or groin; or
to distant parts of the body.
Treatment Option Overview
How cancer of the penis is treated
There are treatments for all patients with
Surgery(taking out the cancer in an operation) Radiation therapy(using high- dose x-raysor other high-energy rays to kill cancer cellsand shrink tumors) Chemotherapy(using drugsto kill the cancer cells) Biological therapy(using the immune systemto fight cancer)
Surgery is the most common treatment of all
Wide local excisiontakes out only the cancer and some normal tissueon either side. Mohs microsurgeryis an operation that removes the cancer and as little normal tissue as possible. During this surgery, the doctor uses a microscope to look at the cancerousarea to make sure all the cancer cells are removed. Laser surgeryuses a narrow beam of light to remove cancer cells. Cryosurgeryuses an instrument to freeze and destroy abnormaltissue, such as carcinoma in situ. This type of treatment is also called cryotherapy. Circumcisionis an operation that removes the foreskin. Amputationof the penis is an operation that takes out all or part of the penis. It is the most common and most effective treatment of cancer of the penis. In a partial penectomy, part of the penis is taken out. In a total penectomy, the whole penis is removed. Lymph nodesin the groinmay be taken out during surgery.
Radiation therapy uses x-rays or other high-energy rays to kill cancer cells and shrink tumors.
Chemotherapy uses drugs to kill cancer cells.
Biological therapy tries to get the body to fight cancer. It uses materials made by the body or made in a laboratory to boost, direct, or restore the body?s natural defenses against disease. Biological treatment is sometimes called biological response modifier (BRM) therapy.
Treatment by stage
Treatment of cancer of the penis depends on the stage of the disease, the type of disease, and the patient?s age and overall condition.
Stage 0 Penile Cancer
Microsurgery. Topicaltreatment using fluorouracilor imiquimod. Laser surgery. Cryosurgery.
Stage I Penile Cancer
Amputationof the penis(partial penectomy). Lymph nodesin the groinmay also be removed. Externalor internal radiation therapy. Mohs microsurgery.
Stage II Penile Cancer
Surgery(partial or total amputationof the peniswith or without removal of lymph nodesin the groin). Radiation therapyfollowed by surgery.
clinical trialof laser surgery.
Stage III Penile Cancer
Surgery( amputationof the penisand removal of lymph nodesin the groin) with or without radiation therapy.
clinical trialof radiosensitizers.
A clinical trial of
chemotherapybefore or after surgery.
Stage IV Penile Cancer
Surgery. Radiation therapy.
clinical trialof chemotherapybefore or after surgery.
A clinical trial of chemotherapy combined with radiation therapy.
Recurrent Penile Cancer
Surgery( amputationof the penis). Radiation therapy.
clinical trialof biologic therapy.
A clinical trial of
Changes to This Summary (04/19/2006)
Changes were made to this summary to match those made to the health professional version.
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