Endometrial Cancer Screening (PDQ�)
What is screening?
Scientists are trying to better understand which people are more likely to get certain types of cancer. They also study the things we do and the things around us to see if they cause cancer. This information helps doctors recommend who should be screened for cancer, which screening tests should be used, and how often the tests should be done.
It is important to remember that your doctor does not necessarily think you have cancer if he or she suggests a screening test. Screening tests are given when you have no cancer symptoms.
If a screening test result is abnormal, you may need to have more tests done to find out if you have cancer. These are called
General Information About Endometrial Cancer
Endometrial cancer is a disease in which malignant (cancer) cells form in the tissues of the endometrium.
See the following
Endometrial Cancer Treatment
Endometrial Cancer Prevention
In the United States, endometrial cancer is the most common invasive cancer of the female reproductive system.
Endometrial cancer is diagnosed most often in postmenopausal women at an average age of 60 years.
Since 1992, the number of white women diagnosed with endometrial cancer has remained stable, but the number of new cases in black women has increased slightly. Endometrial cancer occurs more often in white women than in black women. When endometrial cancer is
Health history and certain medicines can affect the risk of developing endometrial cancer.
Anything that increases your chance of getting a disease is called a
tamoxifenfor treatment or prevention of breast cancer.
estrogenalone. (Taking estrogen in combination with progesteronedoes not appear to increase the risk of endometrial cancer.)
Eating a high-fat diet.
Never giving birth.
menstruationat an early age.
menopauseat an older age.
genefor hereditary non-polyposis colon cancer(HNPCC).
Endometrial Cancer Screening
Tests are used to screen for different types of cancer.
Endometrial cancer is usually found early.
There is no standard or routine screening test for endometrial cancer.
Screening for endometrial cancer is under study and there are screening clinical trials taking place in many parts of the country. Information about ongoing clinical trials is available from the NCI Web site.
Tests that may detect (find) endometrial cancer are being studied:
Pap tests are not used to screen for endometrial cancer; however, Pap test results sometimes show signs of an abnormal
No studies have shown that screening by transvaginal ultrasound (TVU) lowers the number of deaths caused by endometrial cancer.
TVU is commonly used to examine women who have abnormal vaginal bleeding. For women who have or are at risk for
The use of
It has not been proven that screening by endometrial sampling (biopsy) lowers the number of deaths caused by endometrial cancer.
Endometrial sampling is the removal of tissue from the endometrium by inserting a brush,
Endometrial sampling is commonly used to examine women who have abnormal vaginal bleeding. If you have abnormal vaginal bleeding, check with your doctor.
Risks of Endometrial Cancer Screening
Screening tests have risks.
The risks of endometrial cancer screening tests include the following:
Finding endometrial cancer may not improve health or help a woman live longer.
Screening may not improve your health or help you live longer if you have
Some cancers never cause
False-negative test results can occur.
Screening test results may appear to be normal even though endometrial cancer is present. A woman who receives a
False-positive test results can occur.
Screening test results may appear to be
Side effects may be caused by the test itself.
Side effects that may be caused by screening tests for endometrial cancer include:
Puncture of the
If you have any questions about your risk for endometrial cancer or the need for screening tests, check with your doctor.
Get More Information From NCI
For more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.
The NCI's LiveHelp� online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer.
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There are also many other places to get materials and information about cancer treatment and services. Hospitals in your area may have information about local and regional agencies that have information on finances, getting to and from treatment, receiving care at home, and dealing with problems related to cancer treatment.
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Changes to This Summary (07/29/2011)
Changes were made to this summary to match those made to the health professional version.
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PDQ is a comprehensive cancer database available on NCI's Web site.
PDQ is the National Cancer Institute's (NCI's) comprehensive cancer information database. Most of the information contained in PDQ is available online at NCI's Web site. PDQ is provided as a service of the NCI. The NCI is part of the National Institutes of Health, the federal government's focal point for biomedical research.
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PDQ also contains information on clinical trials.
A clinical trial is a study to answer a scientific question, such as whether a method of finding cancer earlier can help people to live longer. Trials are based on past studies and what has been learned in the laboratory. Each trial answers certain scientific questions in order to find new and better ways to help cancer patients and those who are at risk for cancer. During screening clinical trials, information is collected about the effects of a new screening method and how well it works. If a clinical trial shows that a new method is better than one currently being used, the new method may become "standard." People who are at high risk for a certain type of cancer may want to think about taking part in a clinical trial.
Listings of clinical trials are included in PDQ and are available online at NCI's Web site. Descriptions of the trials are available in health professional and patient versions. Many cancer doctors who take part in clinical trials are also listed in PDQ. For more information, call the Cancer Information Service 1-800-4-CANCER (1-800-422-6237).