From research that focuses on liver disease treatment to reducing or preventing organ rejection, the Loma Linda University Medical Center (LLUMC) Transplantation Institute aims to revolutionize the field of transplantation by expanding the knowledge of healthcare professionals worldwide.

Patients who take part may be helped personally by the treatment(s) they receive. They get up-to-date care from experts, and they receive either a new treatment being tested or the best available standard treatment. Through clinical trials, we structure research studies to answer specific questions to evaluate the safety and effectiveness of new treatments, devices, vaccines and procedures. Clinical trials also give transplant patients access to the latest generation of therapies. Currently, we conduct clinical trials in the following transplant areas:

Heart

  • No active clinical trials at this time.

Bone Marrow / Stem Cell

  • No active clinical trials at this time.

Kidney

  • Clinical Trial Description:
  • A phase IV, non-interventional, multi-center, open-label, prospective, observational study of the safety, effectiveness, tolerability and compliance of immunosuppressive regimen using mycophenolic acid to treat de novo renal transplant patients in routine clinical practice. Clinical Trial Description:
    Monitoring ImmuKnow levels in renal transplant patients and tailoring immunosuppression to minimize risk of immunosupression-related morbidities and mortalities.
  • Clinical Trial Description:
    A prospective, open-label, randomized trial comparing Prograf® and Neoral® use in kidney transplant recipients of Hispanic ethnicity.
  • Clinical Trial Description:
    Examination of etiology and physiopathology of nephrogenic fibrosing dermopathy (NFD)/nephrogenic systemic fibrosis (NSF).

Pancreas

  • No active clinical trials at this time.

Liver

  • Clinical Trial Description:
    Randomized controlled trial of transarterial chemoembolization versus proton beam radiotherapy for the treatment of hepatocellular carcinoma. Although surgical resection and liver transplantation are the only treatments that enable prolonged survival in patients with hepatocellular carcinoma (HCC), the majority of HCC patients presents with advanced disease and do not undergo resective or ablative therapy. Patients should undergo formal multidisciplinary evaluation prior to initiating any such treatment in order to individualize the best available options.
  • Clinical Trial Description:
    Randomized controlled trial of proton beam radiotherapy plus Sorafenib vs. Sorafenib for patients with hepatocellular carcinoma exceeding San Francisco criteria.
  • Clinical Trial Description:
    Prospective observational study on predictors of early on-treatment response and sustained virological response in a cohort of treatment naïve HCV-infected patients treated with pegylated interferons.
  • Clinical Trial Description:
    Multi-center, randomized, open-labeled, controlled study of the treatment’s effectiveness with once weekly Pegasys® plus daily Copegus® with or without concomitant pioglitazone (Actos®) on early viral kinetics in treatment-naive patients with chronic hepatitis C (genotype-1 HCV infection) and insulin resistance.
  • Clinical Trial Description:
    Observational prospective registry of the efficacy, safety and adherence to therapy of Infergen® (Interferon Alfacon-1) in patients chronically infected with Hepatitis C virus (Protocol #: CIFN-003).
  • Clinical Trial Description:
    Global investigation of therapeutic decisions in hepatocellular carcinoma and of its treatment with Sorafenib (GIDEON) NX0802.

Contact Us

For more information about clinical trials or to enroll in an individual medical research study, call us toll-free at 1-800-548-3790 or locally at 909-558-3636 or visit our facilities today.

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